diff --git a/internal/api/resolver_mutation_configure.go b/internal/api/resolver_mutation_configure.go
index 29dec27e0..db7bc8995 100644
--- a/internal/api/resolver_mutation_configure.go
+++ b/internal/api/resolver_mutation_configure.go
@@ -5,6 +5,7 @@ import (
 	"errors"
 	"fmt"
 	"path/filepath"
+	"regexp"
 
 	"github.com/stashapp/stash/internal/manager"
 	"github.com/stashapp/stash/internal/manager/config"
@@ -227,10 +228,22 @@ func (r *mutationResolver) ConfigureGeneral(ctx context.Context, input ConfigGen
 	}
 
 	if input.Excludes != nil {
+		for _, r := range input.Excludes {
+			_, err := regexp.Compile(r)
+			if err != nil {
+				return makeConfigGeneralResult(), fmt.Errorf("video exclusion pattern '%v' invalid: %w", r, err)
+			}
+		}
 		c.Set(config.Exclude, input.Excludes)
 	}
 
 	if input.ImageExcludes != nil {
+		for _, r := range input.ImageExcludes {
+			_, err := regexp.Compile(r)
+			if err != nil {
+				return makeConfigGeneralResult(), fmt.Errorf("image/gallery exclusion pattern '%v' invalid: %w", r, err)
+			}
+		}
 		c.Set(config.ImageExclude, input.ImageExcludes)
 	}
 
@@ -464,6 +477,12 @@ func (r *mutationResolver) ConfigureScraping(ctx context.Context, input ConfigSc
 	}
 
 	if input.ExcludeTagPatterns != nil {
+		for _, r := range input.ExcludeTagPatterns {
+			_, err := regexp.Compile(r)
+			if err != nil {
+				return makeConfigScrapingResult(), fmt.Errorf("tag exclusion pattern '%v' invalid: %w", r, err)
+			}
+		}
 		c.Set(config.ScraperExcludeTagPatterns, input.ExcludeTagPatterns)
 	}