diff --git a/spacy/ml/callbacks.py b/spacy/ml/callbacks.py
index 18290b947..3b60ec2ab 100644
--- a/spacy/ml/callbacks.py
+++ b/spacy/ml/callbacks.py
@@ -89,11 +89,14 @@ def pipes_with_nvtx_range(
                 types.MethodType(nvtx_range_wrapper_for_pipe_method, pipe), func
             )
 
-            # Try to preserve the original function signature.
+            # We need to preserve the original function signature so that
+            # the original parameters are passed to pydantic for validation downstream.
             try:
                 wrapped_func.__signature__ = inspect.signature(func)  # type: ignore
             except:
-                pass
+                # Can fail for Cython methods that do not have bindings.
+                warnings.warn(Warnings.W122.format(method=name, pipe=pipe.name))
+                continue
 
             try:
                 setattr(
diff --git a/spacy/pipeline/pipe.pyx b/spacy/pipeline/pipe.pyx
index 4e3ae1cf0..8407acc45 100644
--- a/spacy/pipeline/pipe.pyx
+++ b/spacy/pipeline/pipe.pyx
@@ -1,4 +1,4 @@
-# cython: infer_types=True, profile=True
+# cython: infer_types=True, profile=True, binding=True
 from typing import Optional, Tuple, Iterable, Iterator, Callable, Union, Dict
 import srsly
 import warnings
diff --git a/spacy/pipeline/trainable_pipe.pyx b/spacy/pipeline/trainable_pipe.pyx
index 76b0733cf..3f0507d4b 100644
--- a/spacy/pipeline/trainable_pipe.pyx
+++ b/spacy/pipeline/trainable_pipe.pyx
@@ -1,4 +1,4 @@
-# cython: infer_types=True, profile=True
+# cython: infer_types=True, profile=True, binding=True
 from typing import Iterable, Iterator, Optional, Dict, Tuple, Callable
 import srsly
 from thinc.api import set_dropout_rate, Model, Optimizer