diff --git a/numpy/core/src/multiarray/alloc.c b/numpy/core/src/multiarray/alloc.c
index f8305d115..369a14012 100644
--- a/numpy/core/src/multiarray/alloc.c
+++ b/numpy/core/src/multiarray/alloc.c
@@ -277,3 +277,9 @@ PyDataMem_RENEW(void *ptr, size_t size)
     }
     return result;
 }
+
+NPY_NO_EXPORT void npy_init_cache() {
+  memset(datacache, 0, sizeof(cache_bucket) * NBUCKETS);
+  memset(dimcache, 0, sizeof(cache_bucket) * NBUCKETS_DIM);
+  _PyDataMem_eventhook = NULL;
+}
diff --git a/numpy/core/src/multiarray/alloc.h b/numpy/core/src/multiarray/alloc.h
index 2b69efc35..10069503d 100644
--- a/numpy/core/src/multiarray/alloc.h
+++ b/numpy/core/src/multiarray/alloc.h
@@ -33,4 +33,7 @@ npy_free_cache_dim_array(PyArrayObject * arr)
     npy_free_cache_dim(PyArray_DIMS(arr), PyArray_NDIM(arr));
 }
 
+NPY_NO_EXPORT void
+npy_init_cache(void);
+
 #endif
diff --git a/numpy/core/src/multiarray/multiarraymodule.c b/numpy/core/src/multiarray/multiarraymodule.c
index 8e7352e4f..a713679e8 100644
--- a/numpy/core/src/multiarray/multiarraymodule.c
+++ b/numpy/core/src/multiarray/multiarraymodule.c
@@ -4747,6 +4747,8 @@ PyMODINIT_FUNC initmultiarray(void) {
         goto err;
     }
 
+    npy_init_cache();
+
 #if defined(MS_WIN64) && defined(__GNUC__)
   PyErr_WarnEx(PyExc_Warning,
         "Numpy built with MINGW-W64 on Windows 64 bits is experimental, " \