diff --git a/kombu/transport/SQS.py b/kombu/transport/SQS.py
index 0c8d1ee4..7d3fa0cc 100644
--- a/kombu/transport/SQS.py
+++ b/kombu/transport/SQS.py
@@ -766,34 +766,30 @@ class Channel(virtual.Channel):
         return c
 
     def _handle_sts_session(self, queue, q):
+        region = q.get('region', self.region)
         if not hasattr(self, 'sts_expiration'):  # STS token - token init
-            sts_creds = self.generate_sts_session_token(
-                self.transport_options.get('sts_role_arn'),
-                self.transport_options.get('sts_token_timeout', 900))
-            self.sts_expiration = sts_creds['Expiration']
-            c = self._predefined_queue_clients[queue] = self.new_sqs_client(
-                region=q.get('region', self.region),
-                access_key_id=sts_creds['AccessKeyId'],
-                secret_access_key=sts_creds['SecretAccessKey'],
-                session_token=sts_creds['SessionToken'],
-            )
-            return c
+            return self._new_predefined_queue_client_with_sts_session(queue, region)
         # STS token - refresh if expired
         elif self.sts_expiration.replace(tzinfo=None) < datetime.utcnow():
-            sts_creds = self.generate_sts_session_token(
-                self.transport_options.get('sts_role_arn'),
-                self.transport_options.get('sts_token_timeout', 900))
-            self.sts_expiration = sts_creds['Expiration']
-            c = self._predefined_queue_clients[queue] = self.new_sqs_client(
-                region=q.get('region', self.region),
-                access_key_id=sts_creds['AccessKeyId'],
-                secret_access_key=sts_creds['SecretAccessKey'],
-                session_token=sts_creds['SessionToken'],
-            )
-            return c
+            return self._new_predefined_queue_client_with_sts_session(queue, region)
         else:  # STS token - ruse existing
+            if queue not in self._predefined_queue_clients:
+                return self._new_predefined_queue_client_with_sts_session(queue, region)
             return self._predefined_queue_clients[queue]
 
+    def _new_predefined_queue_client_with_sts_session(self, queue, region):
+        sts_creds = self.generate_sts_session_token(
+            self.transport_options.get('sts_role_arn'),
+            self.transport_options.get('sts_token_timeout', 900))
+        self.sts_expiration = sts_creds['Expiration']
+        c = self._predefined_queue_clients[queue] = self.new_sqs_client(
+            region=region,
+            access_key_id=sts_creds['AccessKeyId'],
+            secret_access_key=sts_creds['SecretAccessKey'],
+            session_token=sts_creds['SessionToken'],
+        )
+        return c
+
     def generate_sts_session_token(self, role_arn, token_expiry_seconds):
         sts_client = boto3.client('sts')
         sts_policy = sts_client.assume_role(
diff --git a/t/unit/transport/test_SQS.py b/t/unit/transport/test_SQS.py
index b82be5aa..b6a1d6ae 100644
--- a/t/unit/transport/test_SQS.py
+++ b/t/unit/transport/test_SQS.py
@@ -996,6 +996,34 @@ class test_Channel:
         # Assert
         mock_generate_sts_session_token.assert_not_called()
 
+    def test_sts_session_with_multiple_predefined_queues(self):
+        connection = Connection(transport=SQS.Transport, transport_options={
+            'predefined_queues': example_predefined_queues,
+            'sts_role_arn': 'test::arn'
+        })
+        channel = connection.channel()
+        sqs = SQS_Channel_sqs.__get__(channel, SQS.Channel)
+
+        mock_generate_sts_session_token = Mock()
+        mock_new_sqs_client = Mock()
+        channel.new_sqs_client = mock_new_sqs_client
+        mock_generate_sts_session_token.return_value = {
+            'Expiration': datetime.utcnow() + timedelta(days=1),
+            'SessionToken': 123,
+            'AccessKeyId': 123,
+            'SecretAccessKey': 123
+        }
+
+        channel.generate_sts_session_token = mock_generate_sts_session_token
+
+        # Act
+        sqs(queue='queue-1')
+        sqs(queue='queue-2')
+
+        # Assert
+        mock_generate_sts_session_token.assert_called()
+        mock_new_sqs_client.assert_called()
+
     def test_message_attribute(self):
         message = 'my test message'
         self.producer.publish(message, message_attributes={